Home | Online Registration | Registration Form | BSAAM's Organizer | BSAAM's Sponsor | London Accommodation Info | Contact Us
AACL AACL AACL AACL
BSAAM Logo
AACL Logo
BSAAM's Anti Ageing Conference London 2017
Follow us on ...
Facebook  Twitter
Conference Information
2017 Program
2017 Speaker List
2017 Pre-Conference Workshops
2017 Exhibitors Form
2017 Press Form
2017 Peer Review Board Members
   
Delegate Information
Invitation Letter for Visas
2017 Registration Form
2017 VENUE: The Kensington Town Hall - MAP
Nearby London Accommodations
   
A4M Board Certification
  American Board Of Anti-Aging/Regenerative Medicine (ABAARM)
   
Past Conference Information
  2016
2016 Speakers and Presentations
2016 Programme
2016 Exhibitors
2016 Moderators
BSAAM's AACL 2016 Peer Review Board Members
  2015
2015 Speakers and Presentations
2015 Programme
2015 Exhibitors
2015 Moderators
BSAAM's AACL 2015 Peer Review Board Members
  2014
2014 Speakers and Presentations
2014 Programme
2014 Exhibitors
2014 Moderators
2014 Peer Review Board Members
2014 Aesthetic Peer Review Board Members
  2013
2013 Speakers and Presentations
2013 Programme
2013 Exhibitors
2013 Moderators
2013 Peer Review Board Members
2013 Aesthetic Peer Review Board Members
  2012
2012 Speakers and Presentations
2012 Programme
2012 Exhibitors
2012 Moderators
2012 Peer Review Board Members
2012 Aesthetic Peer Review Board Members
  2011
2011 Speakers and Presentations
2011 Programme
2011 Exhibitors
2011 Moderators
2011 Peer Review Board Members
2011 Aesthetic Peer Review Board Members
  2010
2010 Conference Manual
2010 Speakers and Presentations
2010 Programme
2010 Exhibitors
2010 Moderators
2010 Peer Review Board Members
2010 Aesthetic Peer Review Board Members
  2009
Programme for the 2009
Exhibitors for the 2009
Speakers for the 2009
2009 Peer Review Board Members
2009 Aesthetic Peer Review Board Members
  2008
Programme for 2008
Exhibitors for 2008
Speakers for 2008
2008 Peer Review Board Members
2008 Aesthetic Peer Review Board Members
  2007
  2007 Speaker List
2007 Speaker Programme
  Pre Conference Workshops
Sept 12 Pre-Conference Workshop Programme
Sept 13 Pre-Conference Workshop Programme
  2007 Peer Review Board Members
  Exhibitors for 2007
  2006
  3rd Annual Anti-Ageing Conference Manual (2006)
Post Review, remarks and photos of 2006
  Programme for 2006
  ISRM2006 Scientific Board Members
  2006 Peer Review Board Members
  Exhibitors 2006
  2005
  Post Review of 2005
  Remarks about 2005
  Peer Review Board of 2005
  Past Speakers 2005
  2004
  Past Speakers 2004
  2002
  Past Speakers Monte Carlo 2002
   
BSAAM's AACL Organizer
BSAAM
BSAAM Affiliates
waaam
   
   
A4M
   
wosaam
AACL Supporters
HB Health
www.hbhealth.com
   
CPD
   
  BANT
   
 
   
 
   
  Sun Chlorella
   
 
   
enerzona
   
BHMA
   
WOCPM
   
FACE
   
IAAS
   
Dole
   
 
   
 
   
   

AACL 2012 Speaker

KhavinsonProf Vladimir Khavinson
President of the International Association of Gerontology and Geriatrics, European Region; Vice–President of the Gerontological Society of the Russian Academy of Sciences, Director of the Saint-Petersburg Institute of Bioregulation and Gerontology, Member of the Russian Academy of Medical Sciences, the main specialist in gerontology and geriatrics of the Health Committee and adviser of the Committee for Social Policy of the Government of St. Petersburg.

Since 1971 V. Khavinson has been engaged in studying of the role of peptides in regulation of the mechanisms of ageing, design, preclinical and clinical study of new peptide geroprotectors. His 35-year long investigations resulted in elaboration of a method for complex application of peptide bioregulators to slow down ageing and increase average life span. 6 peptide pharmaceuticals and 36 biologically active supplements developed by V. Khavinson have been introduced into clinical practice.

V. Khavinson is the author of over 700 publications, however, the major achievements are summarized in his books “Gerontological aspects of genome peptide regulation” (Karger AG, 2005) and “Peptides and Ageing” (NEL, 2002). He is the author of 189 Russian and International patents.

It is thanks to participatory efforts of V. Khavinson that the scientific specialty «Gerontology and Geriatrics» was adopted in the Russian Federation on the governmental level in 2001. An Academic Council for upholding PhD and Doctorate thesis in gerontology and geriatrics was organized at the Institute immediately. Besides professionals from Russia, doctors from other countries defend dissertations in gerontology in this Council. Over 160 theses have been defended at this Council since then.

Three IAGG-ER Congresses were organized and held under his personal supervision. These are: the 2nd European Congress of IAGG on Biogerontology in 2000 in St. Petersburg, the 6th European Congress of IAGG on Clinical Gerontology in 2002 in Moscow and the 6th European Congress of IAGG in 2007 in St. Petersburg.

The Russian Gerontological Society issues 2 scientific Journals – «Advances in Gerontology» and «Clinical Gerontology». V. Khavinson is a member of the Editorial Boards of both Journals and a Deputy Editor-in-Chief of “Advances…”. «Advances in Gerontology» is indexed in Index Medicus/Medline and is be published in the English language by Springer Verlag starting from 2011. The informational instrument of the Society is its bulletin «Herald of the Russian Gerontological Society». It has been published since 1996.

In 2009, the Institute headed by him was designated an IAGG Collaborating Centre. In 2010, the Institute was given a Special Consultative Status of the UN ECOSOC. In 2011, it was enrolled in the IAGG’s Global Ageing Research Network (GARN).

He was the first to organize an International training seminar in collaboration with United Nations Department for Social and Economic Affairs related to formulation and implementation of state policy in the countries of Eastern Europe and Middle Asia. A very important initiative launched by him as a current Chair of the IAGG-ER Biological Section is a special issue of “Biogerontology” prepared together with the Secretary of the IAGG-ER Prof. Suresh Rattan, Editor-in-Chief of the Journal on the occasion of the 7th European Congress of IAGG in Bologna (14-17 April, 2010). It contains articles presented by National European Gerontological Societies providing an overview of the state of biogerontological research in various countries in Europe.

According to the initiative of V. Khavinson the Executive Committee of the IAGG ER has instituted the Award of the IAGG ER «For Advances in Gerontology and Geriatrics». The aims of this Award are to elevate the prestige and significance of gerontological science and to secure public acknowledgement of the excellence and achievements of gerontologists in Europe in the three following disciplines: biological, clinical and social & behavioural sciences.

Design and funding of the award has been undertaken by the Saint Petersburg Institute of Bioregulation and Gerontology.

Honors and awards:

  • Honorary title “ Honored Inventor of the Russian Federation”, 1988
  • “The USSR Council of Ministers’ Prize” for the introduction and promotion of new

       highly efficient peptide bioregulators in health care and veterinary practice, 1990

  • The Russian Academy of Sciences Prize, 1991
  • The State Scientific Grants of the Russian Academy of Sciences for outstanding scientists, 1994, 1997
  • P.Kapitsa’ Memorial medal “Author of Scientific Discovery”, 1996
  • The Ukrainian Academy of Medical Sciences Prize, 2003
  • P.Ehrlich Silver Medal for outstanding  achievements in preventive and social medicine, Europaische Akademie  der Naturwissenschaften, Hannover, 2006
  • Award of the State Duma of the Russian Federation for the best project represented at the Economy Forum in 2007
  • Honorary title «Honored Scientist of the Russian Federation», 2007
  • Prize of the Ukrainian National Academy of Sciences  for the monograph “The Pineal Gland: routes of correction in ageing”, 2010

Member of Societies:

  • Gerontological Society of the Russian Academy of Sciences (since 1994 Vice-President)
  • Italian Academy of Economics and Social Sciences, active member (since 1996)
  • The Gerontological Society of America, active member (since 1996)
  • Research and Medical Society of Gerontologists and Geriatricians of the Ukraine,

      Honorary member  (since 2000)

  • Member of the Expert Council of the Committee for promoting healthy life style

      of the Public Chamber (since 2006)

  • President of the Biological Section of the IAGG ER  (2007-2011) 
  • President of the International Association of Gerontology and Geriatrics, European Region (since 2011)

Member of Editorial Boards of the Journals:

  • Advances  in Gerontology” (St.Petersburg);
  • “Bulletin of Experimental Biology and Medicine” (Moscow)
  • “Clinical Gerontology” (Moscow)
  • “Cytokines and Inflammation” (St.Petersburg)
  • “Geronto-Geriatrics” (Mexico)
  • “Herald of Gerontological. Society of the Russian Acad.of Sci.”(St.Petersburg)
  • “Herald of the Russian Acad. of Natural Sci.” (St.Petersburg)
  • “Medical Acad. Journ.” (St.Petersburg)
  • “Neuroendocrinology Letters” (Stockholm) – Honorary Director

 

2012 - Epigenetic mechanisms of increasing the organism vital resource

Peptides are able to regulate gene expression. In transgenic mice, they suppressed 2-4-fold the expression of the HER-2/neu mammary gland cancer gene. The peptides administered increase IL-2 and c-fos genes transcription in lymphocytes and various structures of hypothalamus. The mechanisms of the peptide action are associated with chromatin activation in blood lymphocytes of aged patients. Human fibroblasts treated with peptides showed the telomerase activity induction and a 2.5-fold increase in the mean telomere length. Peptides increased the number of cell divisions by 42.5% (showed the overcoming of the Hayfiick's limit) and the lifespan of rats by about 30-40%.

Fluorescent FITC-labeled peptides penetrate into HeLa cells and their compartments including nucleus and nucleolus and, therefore, they may interact there with both DNA and RNA. In vitro, peptides investigated bind to double- and single-stranded deoxyribooligonucleotides containing CNG and CG sequences that are target sites for DNA methylation in eukaryotes. Peptide binding depends on the cytosine methylation status of oligos and DNA. Peptides modulate specifically the action of eukaryotic endonucleases depending on DNA methylation status. Site-specific peptide binding with DNA protects DNA against endonuclease hydrolysis. Their binding to CNG or CG sites in gene promoters should prevent a methylation of these sites with respective DNA-methyltransferases and leave promoters unmethylated that is crucial for activation of most genes. This is a one of the most probable mechanisms of regulation of transcription with short peptides. Peptide binding with DNA is modulated by H1 histone.

Treatment of aged and senile people with peptides improved their physiological functions and decreased the lethality by 44-49% in a period of 15-year clinical observation.
Thus, specific peptide-DNA interactions control epigenetically the cell genetic functions and can be responsible for homeostasis recovery and life-span prolongation. They seem to play an important role even at earliest stages of life origin and in evolution.

 

Home | Online Registration | Registration Form | BSAAM's Organizer | BSAAM's Sponsor | London Accommodation Info | Contact Us
BSAAM's Anti Ageing Conference London, 38 Regent on the River
William Morris Way London SW6 2UT, United Kingdom
Tel: +44 (0)79 7317 3478  Fax: +44 (0)20 7491 0410
Emails :
london@antiageingconference.com
mariasomers@bsaam.com